Breaking the Cycle of OCD: Effective Treatment Strategies and Techniques
Mental Health Awareness Series
Dear Readers,
Welcome to Science Simplified! If you’re just discovering Science Simplified Newsletter and curious about the types of article we offer, please click here for a glimpse of what to expect.
This article will provide a detailed overview of the various strategies used in the management of Obsessive-Compulsive Disorder (OCD). This article serves as a follow-up to our previous discussion on the Science of OCD. We will examine the most effective treatment options available, including therapy and medication, as well as lifestyle changes that can help manage symptoms. Additionally, we will discuss the challenges associated with OCD management and provide practical tips for those living with OCD. In addition, we will offer recommendations for additional resources to further educate readers on the topic.
This article is intended for educational purposes only and is not intended to serve as a means of self-diagnosis or self-treatment for OCD.
If you haven’t yet subscribed to the Science Simplified newsletter, we invite you to do so. Just enter your email address below, and you’ll be among the first to know when we publish new content.
Breaking the Cycle of OCD
OCD, like many other mental illnesses, carries a significant social stigma, leading many individuals to suffer in silence. Increasing awareness and understanding of OCD and improving access to care can make a meaningful difference in the lives of those affected by this disorder. Fortunately, there is hope. A variety of OCD treatment strategies, including therapy, medication, or a combination of both, can help individuals manage their symptoms and regain control over their lives. Research indicates that up to 70% of individuals with OCD can achieve remission through appropriate treatment. For those with severe symptoms, there are additional treatment options available.
We encourage you to explore this article to learn more about the available OCD treatment strategies and how they can help you or someone you know manage this disorder.
Effective Treatment Strategies for OCD
Therapy selection for OCD patients typically considers multiple factors, including OCD severity as measured by scales like the Yale-Brown Obsessive-Compulsive Scale (YBOCS). The YBOCS is a widely used tool for rating OCD severity in adults and children. It evaluates overall symptoms from the past week and scores ≥ 16 indicate clinically significant OCD. However, other factors such as patient preferences, treatment history, the presence of co-occurring disorders, and the availability of resources also play a role in determining the most appropriate therapy for each individual.
1. First-Line Treatment
1.1 Cognitive Behavioral Therapy
The most effective treatment for OCD is a form of talking therapy called Cognitive Behavioural Therapy (CBT). CBT is typically done by a licensed mental health professional (such as a psychologist, social worker, or mental health counselor) in an outpatient setting. This means you visit your therapist’s office at a set appointment time once or a few times a week.
This therapy aims to change maladaptive thinking patterns and behaviors. The therapist helps the individual identify and challenge irrational thoughts and beliefs related to their obsessions and compulsions. This includes recognizing cognitive distortions, such as catastrophizing or overgeneralizing, and replacing them with more balanced thoughts. Homework assignments may be given to practice new skills and encourage behavioral change.
CBT is first-line of treatment and the most effective treatment strategy for OCD. It is structured, goal-oriented therapy with two components:
Exposure and Response Prevention (ERP) and
Cognitive Reappraisal.
ERP involves exposing the individual to their obsessions and then preventing them from performing their compulsions. This helps them learn that their fears are irrational, and that they can tolerate the anxiety without performing the compulsions.
It involves the following steps:
Creating a hierarchy: The therapist and the individual work together to develop a list of feared situations or thoughts related to their obsessions, ranking them by anxiety level.
Gradual exposure: The individual is exposed to the feared situations or thoughts, starting with the least anxiety-provoking item on the hierarchy and gradually moving up to more challenging situations.
Response prevention: The individual is instructed to resist performing compulsions during exposure sessions. This helps them learn that their anxiety will decrease over time, even without engaging in compulsive behaviors, ultimately weakening the association between obsessions and compulsions.
Cognitive Reappraisal focuses on changing the way individuals perceive and react to their obsessive thoughts. The therapy involves identifying and challenging negative or irrational thoughts that contribute to OCD symptoms and replacing them with more positive or rational thoughts. Through cognitive reappraisal, individuals can learn to reduce the power of their obsessive thoughts and better manage their emotional responses to them. The therapy also involves learning new coping mechanisms for managing stress and anxiety, which can trigger OCD symptoms.
When treatment works well, the patient gradually experiences less anxiety form the obsessive thoughts and becomes able to do without the compulsive actions for extended periods of time. The majority of people with OCD (about 7 out of 10) will benefit from either CBT, medication or combination of both.
1.2 Pharmacotherapy
Medications can only be prescribed by a licensed medical professionals (such as your physician or a psychiatrist), who would ideally work together with your therapist to develop a treatment plan.
Selective serotonin reuptake inhibitors (SSRIs) are the first-line pharmacological treatment for OCD. They help regulate serotonin levels in the brain, which may reduce the severity of obsessions and compulsions. SSRIs are associated with many adverse effects but are usually well tolerated. The only other medication which has shown to be consistently effective in OCD is the serotoninergic tricyclic antidepressant clomipramine. Clomipramine has been found to be significantly more effective than placebo in multiple randomised controlled trials (RCTs) and meta-analysis of RCTs.
Some commonly prescribed SSRIs include:
Mode of action of SSRIs:
To understand how SSRIs work, let’s first understand the role of serotonin as a neurotransmitter. Serotonin is a brain messenger chemical that carries signals between nerve cells in the brain and is thought to be involved in regulating many functions, influencing emotions, mood, memory and sleep.
Neurons transmit these chemicals to establish communication; sender nerve cell spits serotonin to receiver nerve cells. In order to allow the receiver nerve to recover and receive the next message, the body has a clever way of removing the extra neurotransmitter from the receptors, and allowing it to be taken back into the originating sender nerve (simply called re-uptake). In some people it’s thought this transporter might works too fast, and may collect all the serotonin before the next cell has heard the signal. To put it simply, their nerve cells are whispering when they should be speaking out loud.
SSRIs work by blocking reuptake serotonin transporters and thus increasing the availability of serotonin in the brain. This simply means with the use of SSRI’s the serotonin stays in the space between the communicating nerve cells longer and increases the chances that the second nerve cell will gets the message.
This increase in serotonin levels has been shown to help reduce the frequency and intensity of obsessions and compulsions, although the exact mechanisms by which this occurs are still being researched. It is important to note that serotonin is just one piece of a complex puzzle, and other neurotransmitters and neural pathways are also likely involved in the development and expression of OCD.
1.3 Medication Augmentation
For some individuals, adding another medication to the existing SSRIs like antipsychotic medications (e.g., risperidone, aripiprazole) or clomipramine (a tricyclic antidepressant), may enhance the therapeutic effect. However, this should be done under close supervision of a healthcare professional due to potential side effects.
2. Treatment strategies for non-responders to first-line treatment

Neuromodulation and Neurosurgery
These treatments may be considered when other approaches have not provided adequate symptom relief.
2.1 Transcranial Magnetic Stimulation (TMS)
TMS is a non-invasive brain stimulation technique that uses magnetic pulses to target specific brain regions associated with OCD.
It is performed using a device called a magnetic coil, which is placed on the scalp over the targeted brain region.
The magnetic pulses generated by the coil pass through the skull and induce electrical currents in the underlying brain tissue, modulating neural activity.
TMS sessions typically last about 20-40 minutes and are conducted daily for several weeks.
The most common side effects are mild, including headaches and scalp discomfort, which usually subside over time.
2.2 Deep Brain Stimulation (DBS)
This treatment is typically reserved for severe, treatment-resistant OCD cases after other options have been exhausted.
The procedure involves implanting electrodes into specific brain regions implicated in the pathology of OCD, such as the subthalamic nucleus, the ventral capsule/ventral striatum, or the nucleus accumbens.
The electrodes are connected to a pulse generator, which is typically implanted under the skin in the chest area.
The pulse generator sends electrical impulses to the targeted brain areas, modulating their activity and alleviating OCD symptoms.
DBS settings can be adjusted noninvasively by a clinician to optimize treatment outcomes.
The most common side effects of DBS include infection, bleeding, and hardware-related complications. However, these risks are generally low.
3. Self-Help Strategies
Lifestyle changes and stress management techniques can also be helpful for managing OCD symptoms. These include regular exercise, adequate sleep, relaxation techniques, and support from friends and family.
Various self-help techniques can be used in conjunction with professional treatment or as standalone strategies to manage OCD symptoms:
Mindfulness and meditation: Developing mindfulness skills can help individuals become more aware of their thoughts and feelings, and learn to respond non-judgmentally and non-reactively to their obsessions.
Regular exercise: Engaging in regular physical activity can help reduce anxiety and improve overall mental well-being.
Sleep hygiene: Ensuring adequate sleep and maintaining a consistent sleep schedule can help improve overall mental health and reduce anxiety levels.
Support groups: Joining a local or online OCD support group can provide a sense of community and opportunities to learn from others who have experienced similar challenges.
4. What doesn’t work for OCD Treatment ?
Relying solely on willpower to suppress obsessions or stop compulsions is generally ineffective and can even exacerbate symptoms.
Similarly, using avoidance strategies or engaging in reassurance-seeking behaviors can reinforce the OCD cycle, making symptoms more persistent and difficult to manage.
It's important to seek professional help and use evidence-based treatments for the best chance of recovery.
5. Recommendations for further reading
The International OCD Foundation (IOCDF) : This organization provides comprehensive information on OCD, including treatment options, research, and support resources.
The National Institute of Mental Health (NIMH): The NIMH provides information on various mental health disorders, including OCD, as well as the latest research and treatment options.
The book "Freedom from Obsessive Compulsive Disorder" by Jonathan Grayson: This self-help book offers guidance on understanding and managing OCD using CBT and ERP techniques.
The book "The Mindfulness Workbook for OCD" by Jon Hershfield and Tom Corboy: This workbook provides practical guidance on using mindfulness techniques to manage OCD symptoms.
The book "Overcoming Obsessive Thoughts" by Christine Purdon and David A. Clark: This self-help book focuses on cognitive therapy techniques for managing OCD.
This article is intended for educational purposes only and is not intended to serve as a means of self-diagnosis or self-treatment for Obsessive-Compulsive Disorder (OCD). If you are experiencing symptoms of OCD, such as obsessive and compulsive thoughts, it is essential to seek proper advice from a medical professional, such as your family physician.
It's important to remember that there is hope for individuals with OCD and their loved ones. With proper diagnosis, evidence-based treatments, and support from family and friends, many people with OCD can lead fulfilling lives and manage their symptoms effectively. By increasing awareness and understanding, we can help reduce stigma, improve access to care, and make a meaningful difference in the lives of those affected by OCD.
Thank you for reading Science Simplified! Did you enjoy this newsletter as much as I did creating it? I thought so! If you want to keep the good vibes going, why not subscribe to this newsletter?
Plus, sharing is caring! Share this newsletter with your friends and help spread the word. We'd love to hear your thoughts and feedback, so leave us a comment below!